Spend some time researching medication adherence and you will inevitably come across this famous quote from former Surgeon General C. Everett Koop: “Medicines don't work on patients who don't take them.” While there are limitations to how much you can help your patients take their medications (after all, you can't take their medications for them), there is a lot you can do to improve the likelihood that they will do so. That's where medication management comes into play.