TRISODIUM CITRATE DIHYDRATE CAS NO.6132-04-3
#tris #hydrochloride
Cas 6132 04 3
Sodium citrate is widely used. Desheng provides analytically pure sodium citrate which is specially used as blood anticoagulant in blood collection tubes. Sodium citrate can be used as anticoagulation for most blood coagulation experiments. It is less toxic to cells and can also be used as one of the components of blood maintenance fluids in blood transfusion experiments.
As one of the leading sodium citrate dihydrate suppliers in China, Desheng develops and produces sodium citrate with a purity of more than 99%, and in the process of blood coagulation, the sodium citrate trisodium salt dihydrate can effectively chelate calcium ions, so that the blood loses the necessary conditions for coagulation. Sodium citrate combines with free calcium to form a sodium citrate complex, thereby depleting calcium to achieve anticoagulant effect. It’s suitable for sodium citrate blood coagulation tube, erythrocyte sedimentation tube, etc.
Sodium Citrate Details
Sodium citrate specially developed for blood collection tube manufacturers is suitable for the collection and preparation of routine blood coagulation test items, and realizes closed processing of erythrocyte sedimentation rate samples through different ratios, which is suitable for clinical erythrocyte sedimentation rate detection.
Since sodium citrate has a wide range of applications, it is less used as an additive for blood collection tubes. Desheng blood collection tube additive series is specially developed and produced for blood collection tube manufacturers, which can meet the needs of all blood collection tube additives, and the product quality meets the highest standards. standard.
Desheng's Advantages In Sodium Citrate:
There is a professional production and R&D team with rich product knowledge and more stable performance, which can effectively solve any problems encountered during use;
The source manufacturer, with high daily output and stable supply, can deliver goods immediately to meet the purchase demand;
With a professional foreign trade team and rich export experience, Desheng's service follows the customer-oriented service. Good customer service is the highest standard of Desheng people. It can effectively communicate and solve the product problems of sodium citrate, and can provide perfect after-sales service;
The purity of Desheng sodium citrate products is as high as 99 or more, and all indicators meet the requirements of the highest international standards.
Application Of Sodium Citrate As Blood Anticoagulant
Sodium citrate can be used as an anticoagulant and a blood transfusion agent by using the characteristics of citrate root and calcium ions to form a soluble complex, and to preserve and process blood products;
trinatrium citrate is a glycolysis inhibitor, so it also has anti-tumor effect;
It is also an ideal anticoagulant for hemodialysis patients with high risk of hemodialysis complicated with cerebral hemorrhage and gastrointestinal hemorrhage. Its anticoagulant effect is to regulate anticoagulation by consuming Ca ions.
Sodium Citrate Blood Anticoagulation Principle
Trisodium citrate powder is neutralized with alkali substances, and the combination of citric acid and calcium ions forms a soluble complex, which can effectively relieve the effect of calcium ions on blood coagulation. Blood coagulation is divided into three stages: first, prothrombin activator formation; second, prothrombin activator catalyzes the conversion of prothrombin to thrombin; third, thrombin catalyzes the conversion of fibrinogen to fibrin. In these three stages, the participation of calcium ions is required, so once the chelated calcium ions are removed, the blood loses the necessary conditions for coagulation. When taking fresh blood clinically, adding some sodium citrate can prevent blood coagulation, so sodium citrate is called blood anticoagulant.
Instructions for sodium citrate application
Sodium citrate dihydrate powder needs to be prepared into a solvent with deionized water before use, and needs to be evenly sprayed on the wall of the vacuum blood collection tube when using;
The configured vacuum blood collection tube needs to be gently turned upside & down 5 to 8 times after collecting blood samples, so that the blood and anticoagulant are fully mixed to avoid partial blood coagulation.
Sodium Citrate Precautions
The sodium citrate dihydrate powder is easily to absorb moisture in the air, so it should be sealed and stored. If it is accidentally exposed to humid air and has slight deliquescence, it can be heated to about 40 degrees and placed in dry air to lose crystal water and dry it.
The use of sodium citrate must be carried out in accordance with the manufacturer's operating procedures. Solid hydrated or anhydrous substances should be stored in airtight containers and stored in a cool and dry place.
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