Xao tam phan (Paramignya trimera (Oliv.) Guillaum) is a Vietnamese traditionally medicinal plant employed in treating numerous cancers. The preparation of Xao tam phan extracts including solvent type and extraction method have significant effects on extraction efficiency, phytochemical profile and biological activity. This research aimed to look into the effects of 5 various solvents (water, acetonitrile, methanol, ethyl acetate and hexane) and three different extraction methods (conventional, ultrasound-assisted and microwave-assisted) on phytochemical yield and antioxidant capacity of P. trimera root from Vietnam. The outcome indicate that methanol extracted the maximal yield of phytochemicals from P. trimera and exhibited the best antioxidant capacity, with eleven compounds were identified and quantified. Microwave-assisted extraction produced the maximal phytochemical yields (except for total flavonoids) and antioxidant capacity, when compared with conventional and ultrasound-assisted extractions. These data reveal that the usage of methanol and microwave-assisted extraction are suggested for extraction of biologically active phytochemicals from P. trimera root for application within the nutraceutical and/or pharmaceutical industries.
Drying methods, solvents and extraction methods greatly affect the phytochemical compounds and biological activity from plant materials. The aims with this study were to determine the results of numerous drying methods, various solvents and extraction methods for the phytochemical compounds and antioxidant capacity from Xao tam phan (Paramignya trimera) root obtained from Vietnam. The results showed that microwave drying was a powerful method in eliminating water regarding shortest drying time, lowest energy consumption as well as retention of phytochemical compounds and antioxidant capacity through the P. trimera root while methanol and microwave-assisted extraction were the most effective solvent and method for greatest extraction in the phytochemical compounds and antioxidant capacity through the P. trimera root. The findings using this study allow retaining the highest amounts of phytochemical compounds and antioxidant capacity in the P. trimera root for potential application inside the nutraceutical industry.
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