Anti-Cancer Effects Of Xao Tam Phan Paramignya Trimera Methanol Root Extract On Human Cancer Of The Breast





Xao tam phan (Paramignya trimera (Oliv.) Guillaum) is a Vietnamese traditionally medicinal plant found in the treatment of numerous cancers. The preparation of Xao tam phan extracts including solvent type and extraction method have significant effects on extraction efficiency, phytochemical profile and biological activity. This study aimed to research the effects of five various solvents (water, acetonitrile, methanol, ethyl acetate and hexane) and three different extraction methods (conventional, ultrasound-assisted and microwave-assisted) on phytochemical yield and antioxidant capacity of P. trimera root from Vietnam. The final results indicate that methanol extracted the maximal yield of phytochemicals from P. trimera and exhibited the highest antioxidant capacity, with eleven compounds were identified and quantified. Microwave-assisted extraction produced the maximal phytochemical yields (apart from total flavonoids) and antioxidant capacity, in comparison to conventional and ultrasound-assisted extractions. These data demonstrate that the application of methanol and microwave-assisted extraction are suggested for extraction of biologically active phytochemicals from P. trimera root for application in the nutraceutical and/or pharmaceutical industries.




Drying methods, solvents and extraction methods greatly impact the phytochemical compounds and biological activity from plant materials. The aims on this study would determine the effects of numerous drying methods, various solvents and extraction methods for the phytochemical compounds and antioxidant capacity from Xao tam phan (Paramignya trimera) root obtained from Vietnam. The outcome established that microwave drying was a highly effective method in eliminating water with regards to shortest drying time, lowest energy consumption as well as retention of phytochemical compounds and antioxidant capacity through the P. trimera root while methanol and microwave-assisted extraction were the very best solvent and way for greatest extraction from the phytochemical compounds and antioxidant capacity from your P. trimera root. The findings because of this study allow retaining the very best degrees of phytochemical compounds and antioxidant capacity from your P. trimera root for potential application inside the nutraceutical industry.


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