The organ on a chip is a microfluidic culture device that recapitulates the complicated structures and functions associated with the living human organs. The microdevices are composed of a clear flexible polymer that is almost the size of a USB memory stick and comprises hollow microfluidic channels lined up with living human organ cells and human blood vessel cells. These living, three-dimensional cross-sections of the human organs tend to provide a transparent window into their inner workings and the effects that the drugs can have on them, without involving any humans or animals.
The organ on a chip has been designed in order to recreate the natural physiology and mechanical forces that are experienced by the cells within the human body in an accurate manner. The chips are made to be lined up with living human cells and their tiny fluidic channels help in reproducing both blood and/or airflow just as within the human body.
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